The synthesis, analgesic and anti-inflammatory activity of 3-aryl(heteryl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)-acrylonitrile derivatives

The synthesis, analgesic and anti-inflammatory activity of 3-aryl(heteryl)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)-acrylonitrile derivatives

Aim. To synthesize, prove the structure and study the analgesic and anti-inflammatory activities of 3-(het)-aryl-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)acrylonitrile derivatives. Results and discussion. Condensation of 2-methoxy-3,4,5,6-tetrahydro-7H-azepine with cyanoacetic a...

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Bibliographic Details
Main Authors: Serhii A. Demchenko, Yuliia A. Fedchenkova, Serhii A. Tsyhankov, Оleh E. Yadlovskyi, Volodymyr V. Sukhoveev, Tetiana A. Bukhtiarova, Ludmyla S. Bobkova, Anatolii M. Demchenko
Format: Article
Language:English
Published: National University of Pharmacy (Kharkiv, Ukraine) 2020-05-01
Series:Журнал органічної та фармацевтичної хімії
Subjects:
acrylonitrile derivatives
ketorolac
analgesic activity
anti-inflammatory activity
triazoloazepine
Online Access:http://ophcj.nuph.edu.ua/article/view/ophcj.20.193511/206097

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http://ophcj.nuph.edu.ua/article/view/ophcj.20.193511/206097

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