Vaccination with the Surface Proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans Induces Antibodies but Fails to Provide Protection against Buruli Ulcer.

Vaccination with the Surface Proteins MUL_2232 and MUL_3720 of Mycobacterium ulcerans Induces Antibodies but Fails to Provide Protection against Buruli Ulcer.

BACKGROUND:Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a chronic ulcerative neglected tropical disease of the skin and subcutaneous tissue that is most prevalent in West African countries. M. ulcerans produces a cytotoxic macrolide exotoxin called mycolactone, which causes exte...

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Bibliographic Details
Main Authors: Miriam Bolz, Angèle Bénard, Anita M Dreyer, Sarah Kerber, Andrea Vettiger, Wulf Oehlmann, Mahavir Singh, Malcolm S Duthie, Gerd Pluschke
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4746116?pdf=render

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http://europepmc.org/articles/PMC4746116?pdf=render

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