Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity.

Chronic elevation of the sympathetic nervous system has been identified as a major contributor to the complex pathophysiology of hypertension, states of volume overload -such as heart failure- and progressive kidney disease. It is also a strong determinant for clinical outcome. This review focuses o...

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Bibliographic Details
Main Authors: Eva Elisabeth Vink, Peter J. Blankestijn
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00029/full