ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation

ITRAQ-Based Proteomics Analysis Reveals the Effect of Neoliensinine on KCl-Induced Vascular Smooth Muscle Contraction by Inhibiting Regulatory Light Chain Phosphorylation

Smooth muscle (SM) contraction is one of the important physiological functions of the human body, and SM abnormal contraction will induce many diseases. The phosphorylated regulatory light chains (p-RLC) play a decisive role in SM contraction, and dephosphorylation of p-RLC is an effective way to re...

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Bibliographic Details
Main Authors: Guang-Ming Yang, Ke Yan, Peng Wang, Jun-Li Zhang, Zi-Hao Pan, Yang Pan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
vascular smooth muscle relaxation
neoliensinine
Nelumbo nucifera Gaertn
regulatory light chain phosphorylation
iTRAQ
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00979/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00979/full

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