Assessing the emergence and reliability of cognitive decline over the life span in Fisher 344 rats using the spatial water maze

The spatial water maze is routinely used to investigate hippocampal-dependent spatial memory and the biological mechanisms that underlie variability in cognitive decline during aging. The utility of the task for repeated testing in order to examine the trajectory of cognitive decline and to prescree...

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Bibliographic Details
Main Authors: Michael eGuidi, Ashok eKumar, Asha eRani, Thomas C Foster
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00002/full