Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats
<p>Abstract</p> <p>Background</p> <p>The development of analgesic tolerance following chronic morphine administration can be a significant clinical problem. Preclinical studies demonstrate that chronic morphine administration induces spinal gliosis and that inhibition o...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-04-01
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Series: | Molecular Pain |
Online Access: | http://www.molecularpain.com/content/6/1/22 |