An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

An immunoevasive strategy through clinically-relevant pan-cancer genomic and transcriptomic alterations of JAK-STAT signaling components

Abstract Background Since its discovery almost three decades ago, the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) pathway has paved the road for understanding inflammatory and immunity processes related to a wide range of human pathologies including cancer. Several stu...

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Bibliographic Details
Main Authors: Wai Hoong Chang, Alvina G. Lai
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Molecular Medicine
Subjects:
JAK-STAT
Pan-cancer
Tumor immunity
Glioma
Renal cancer
Online Access:http://link.springer.com/article/10.1186/s10020-019-0114-1

Internet

http://link.springer.com/article/10.1186/s10020-019-0114-1

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