Mahuang Decoction Antagonizes Acute Liver Failure via Modulating Tricarboxylic Acid Cycle and Amino Acids Metabolism

Mahuang Decoction Antagonizes Acute Liver Failure via Modulating Tricarboxylic Acid Cycle and Amino Acids Metabolism

Acute liver failure (ALF) is a serious clinical disorder with high fatality rates. Mahuang decoction (MHD), a well-known traditional Chinese medicine, has multiple pharmacological effects, such as anti-inflammation, anti-allergy, anti-asthma, and anti-hyperglycemia. In this study, we investigated th...

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Bibliographic Details
Main Authors: Wenting Liao, Qiwen Jin, Junning Liu, Yiling Ruan, Xinran Li, Yueyue Shen, Zhicheng Zhang, Yong Wang, Shengming Wu, Junying Zhang, Lifeng Kang, Chunyong Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
mahuang decoction
acute liver failure
metabolomics
UPLC-Q-exactive-MS
tricarboxylic acid cycle
amino acids metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.599180/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.599180/full

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