TLR4 polymorphisms seem not to be associated with prediabetes and type 2 diabetes but predispose to diabetic retinopathy; TLR4 polymorphisms in glucose continuum

Objectives. Compared to type 1 diabetes, the role of the immune and autoimmune pathogenetic mechanisms is much less studied in the type 2 diabetes. Toll-like receptors 4 (TLR4) have a leading role in inflammation, insulin resistance, and vascular damage. This study aimed to analyze the relationship...

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Bibliographic Details
Main Authors: Zaharieva ET, Kamenov ZA, Savov AS
Format: Article
Language:English
Published: Sciendo 2017-07-01
Series:Endocrine Regulations
Subjects:
Online Access:https://doi.org/10.1515/enr-2017-0014