Identification of RNA-binding proteins that partner with Lin28a to regulate Dnmt3a expression

Abstract Lin28 is an evolutionary conserved RNA-binding protein that plays important roles during embryonic development and tumorigenesis. It regulates gene expression through two different post-transcriptional mechanisms. The first one is based on the regulation of miRNA biogenesis, in particular t...

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Bibliographic Details
Main Authors: Silvia Parisi, Daniela Castaldo, Silvia Piscitelli, Chiara D’Ambrosio, Giuseppina Divisato, Fabiana Passaro, Rosario Avolio, Alessia Castellucci, Paolo Gianfico, Mariorosario Masullo, Andrea Scaloni, Tommaso Russo
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-81429-8