Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model.

Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model.

Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with HAT. Sterol 14alpha-demethylase (CYP51) is a poten...

Full description

Bibliographic Details
Main Authors: Frédéric-Antoine Dauchy, Mélanie Bonhivers, Nicolas Landrein, Denis Dacheux, Pierrette Courtois, Florian Lauruol, Sylvie Daulouède, Philippe Vincendeau, Derrick R Robinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC5113867?pdf=render

Internet

http://europepmc.org/articles/PMC5113867?pdf=render

Similar Items