Intracoronary Delivery of Human Mesenchymal/Stromal Stem Cells: Insights from Coronary Microcirculation Invasive Assessment in a Swine Model.

Mesenchymal stem/stromal cells have unique properties favorable to their use in clinical practice and have been studied for cardiac repair. However, these cells are larger than coronary microvessels and there is controversy about the risk of embolization and microinfarctions, which could jeopardize...

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Main Authors: António Fiarresga, Márcia F Mata, Sandra Cavaco-Gonçalves, Mafalda Selas, Irina N Simões, Eunice Oliveira, Belmira Carrapiço, Nuno Cardim, Joaquim M S Cabral, Rui Cruz Ferreira, Cláudia L da Silva
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4610677?pdf=render