Anticholinergics boost the pathological process of neurodegeneration with increased inflammation in a tauopathy mouse model

Anticholinergics, and drugs with anticholinergic properties, are widely and frequently prescribed, especially to the elderly. It is well known that these drugs decrease cognitive function and increase the risk of dementia. Although the mechanism of anticholinergic drug-induced cognitive impairment h...

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Bibliographic Details
Main Authors: Yasumasa Yoshiyama, Ayako Kojima, Kimiko Itoh, Tomoyuki Uchiyama, Kimihito Arai
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Neurobiology of Disease
Subjects:
Tau
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611100283X