Modeling of Myotonic Dystrophy Cardiac Phenotypes in Drosophila

Modeling of Myotonic Dystrophy Cardiac Phenotypes in Drosophila

After respiratory distress, cardiac dysfunction is the second most common cause of fatality associated with the myotonic dystrophy (DM) disease. Despite the prevalance of heart failure in DM, physiopathological studies on heart symptoms have been relatively scarce because few murine models faithfull...

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Bibliographic Details
Main Authors: Mouli Chakraborty, Beatriz Llamusi, Ruben Artero
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neurology
Subjects:
cardiac dysfunction
myotonic dystrophy
Muscleblind
CTG expansion
CCTG expansion
Drosophila disease model
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00473/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00473/full

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