An Empirical Bayes Optimal Discovery Procedure Based on Semiparametric Hierarchical Mixture Models

Multiple testing has been widely adopted for genome-wide studies such as microarray experiments. For effective gene selection in these genome-wide studies, the optimal discovery procedure (ODP), which maximizes the number of expected true positives for each fixed number of expected false positives,...

Full description

Bibliographic Details
Main Authors: Hisashi Noma, Shigeyuki Matsui
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2013/568480