An Empirical Bayes Optimal Discovery Procedure Based on Semiparametric Hierarchical Mixture Models
Multiple testing has been widely adopted for genome-wide studies such as microarray experiments. For effective gene selection in these genome-wide studies, the optimal discovery procedure (ODP), which maximizes the number of expected true positives for each fixed number of expected false positives,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2013-01-01
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Series: | Computational and Mathematical Methods in Medicine |
Online Access: | http://dx.doi.org/10.1155/2013/568480 |