LEFTY2 Controls Migration of Human Endometrial Cancer Cells via Focal Adhesion Kinase Activity (FAK) and miRNA-200a

LEFTY2 Controls Migration of Human Endometrial Cancer Cells via Focal Adhesion Kinase Activity (FAK) and miRNA-200a

Background: LEFTY2, a suppressor of cell proliferation, tumor growth, regulator of stemness and embryonic differentiation, is a negative regulator of cancer cell reprogramming. Malignant transformation may lead to migration requiring loss of adhesion and gain of migratory activity. Signaling involve...

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Bibliographic Details
Main Authors: Nour Alowayed, Madhuri S. Salker, Ni Zeng, Yogesh Singh, Florian Lang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-200a
FAK
Migration
Tumor cells
E-cadherin
Online Access:http://prod.karger.com/Article/FullText/447792

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http://prod.karger.com/Article/FullText/447792

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