A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island.
The Helicobacter pylori cag pathogenicity island (cagPAI) encodes a type IV secretion system. Humans infected with cagPAI-carrying H. pylori are at increased risk for sequelae such as gastric cancer. Housekeeping genes in H. pylori show considerable genetic diversity; but the diversity of virulence...
Main Authors: | Patrick Olbermann, Christine Josenhans, Yoshan Moodley, Markus Uhr, Christiana Stamer, Marc Vauterin, Sebastian Suerbaum, Mark Achtman, Bodo Linz |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-08-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2924317?pdf=render |
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