A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island.

A global overview of the genetic and functional diversity in the Helicobacter pylori cag pathogenicity island.

The Helicobacter pylori cag pathogenicity island (cagPAI) encodes a type IV secretion system. Humans infected with cagPAI-carrying H. pylori are at increased risk for sequelae such as gastric cancer. Housekeeping genes in H. pylori show considerable genetic diversity; but the diversity of virulence...

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Bibliographic Details
Main Authors: Patrick Olbermann, Christine Josenhans, Yoshan Moodley, Markus Uhr, Christiana Stamer, Marc Vauterin, Sebastian Suerbaum, Mark Achtman, Bodo Linz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2924317?pdf=render

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http://europepmc.org/articles/PMC2924317?pdf=render

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