Beta-defensins and analogs in Helicobacter pylori infections: mRNA expression levels, DNA methylation, and antibacterial activity.

Beta-defensins and analogs in Helicobacter pylori infections: mRNA expression levels, DNA methylation, and antibacterial activity.

Antimicrobial peptides can protect the gastric mucosa from bacteria, but Helicobacter pylori (H. pylori) can equally colonize the gastric apparatus. To understand beta-defensin function in H. pylori-associated chronic gastritis, we investigated susceptibility, human beta-defensin mRNA expression, an...

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Bibliographic Details
Main Authors: Raffaela Pero, Tiziana Angrisano, Mariarita Brancaccio, Annarita Falanga, Lucia Lombardi, Francesco Natale, Sonia Laneri, Barbara Lombardo, Stefania Galdiero, Olga Scudiero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0222295

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https://doi.org/10.1371/journal.pone.0222295

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