Cellular hnRNPAB binding to viral nucleoprotein inhibits flu virus replication by blocking nuclear export of viral mRNA

Summary: Heterogeneous nuclear ribonucleoproteins (hnRNPs) play critical roles in the nuclear export, splicing, and sensing of RNA. However, the role of heterogeneous nuclear ribonucleoprotein A/B (hnRNPAB) is poorly understood. In this study, we report that hnRNPAB cooperates with nucleoprotein (NP...

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Bibliographic Details
Main Authors: Xingbo Wang, Lulu Lin, Yiye Zhong, Mingfang Feng, Tianqi Yu, Yan Yan, Jiyong Zhou, Min Liao
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001280