Identification of inappropriately reprogrammed genes by large-scale transcriptome analysis of individual cloned mouse blastocysts.

Although cloned embryos generated by somatic/embryonic stem cell nuclear transfer (SECNT) certainly give rise to viable individuals, they can often undergo embryonic arrest at any stage of embryogenesis, leading to diverse morphological abnormalities. In an effort to gain further insights into repro...

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Bibliographic Details
Main Authors: Atsushi Fukuda, Feng Cao, Shinnosuke Morita, Kaori Yamada, Yuko Jincho, Shouji Tane, Yusuke Sotomaru, Tomohiro Kono
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2894852?pdf=render