Tree reconciliation combined with subsampling improves large scale inference of orthologous group hierarchies

Abstract Background An orthologous group (OG) comprises a set of orthologous and paralogous genes that share a last common ancestor (LCA). OGs are defined with respect to a chosen taxonomic level, which delimits the position of the LCA in time to a specified speciation event. A hierarchy of OGs expa...

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Bibliographic Details
Main Authors: Davide Heller, Damian Szklarczyk, Christian von Mering
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-019-2828-z