Bioresolution Production of (2R,3S)-Ethyl-3-phenylglycidate for Chemoenzymatic Synthesis of the Taxol C-13 Side Chain by Galactomyces geotrichum ZJUTZQ200, a New Epoxide-Hydrolase-Producing Strain

A newly isolated Galactomyces geotrichum ZJUTZQ200 strain containing an epoxide hydrolase was used to resolve racemic ethyl 3-phenylglycidate (rac-EPG) for producing (2R,3S)-ethyl-3-phenylglycidate ((2R,3S)-EPG). G. geotrichum ZJUTZQ200 was verified to be able to afford high enantioselectivity in wh...

Full description

Bibliographic Details
Main Authors: Chun Wei, Jinlong Ling, Honglei Shen, Qing Zhu
Format: Article
Language:English
Published: MDPI AG 2014-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/19/6/8067