Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia

Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different times show comparable biological functions in vitro, and in vivo to repair limb ischemia

Abstract Background We have previously demonstrated that a pooled population of bone marrow-derived, allogeneic mesenchymal stromal cells (BMMSC), Stempeucel®-1, produced under good manufacturing practices (GMP) conditions, showed clinical efficacy and safety in patients suffering from critical limb...

Full description

Bibliographic Details
Main Authors: Charan Thej, Sudha Balasubramanian, Mathiyazhagan Rengasamy, Ankita Walvekar, Priyanka Swamynathan, Swathi Sundar Raj, Pradnya Shahani, Siddikuzzaman, Udaykumar Kolkundkar, Raviraja N. Seetharam, Pawan Kumar Gupta, Anish S. Majumdar
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
Pooled mesenchymal stromal cells
Stempeucel®
Multiple bone marrow aspirations
Angiogenesis
Hind limb ischemia
Online Access:https://doi.org/10.1186/s13287-021-02330-9

Internet

https://doi.org/10.1186/s13287-021-02330-9

Similar Items