Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution.

Thousands of human genes contain introns ending in NAGNAG (N any nucleotide), where both NAGs can function as 3' splice sites, yielding isoforms that differ by inclusion/exclusion of three bases. However, few models exist for how such splicing might be regulated, and some studies have concluded...

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Bibliographic Details
Main Authors: Robert K Bradley, Jason Merkin, Nicole J Lambert, Christopher B Burge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3250501?pdf=render