Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages

Species-Dependent Functionality of the Human Cytolytic Fusion Proteins Granzyme B-H22(scFv) and H22(scFv)-Angiogenin in Macrophages

Human cytolytic fusion proteins (hCFPs) are comprised of a specific cell-surface-binding moiety and an effector molecule of human origin. In contrast to common immunotoxins, including bacterial or plant toxins, they are considered not to be immunogenic. Two examples for human pro-apoptotic effector...

Full description

Bibliographic Details
Main Authors: Theo Thepen, Stefan Barth, Rainer Fischer, Michael Huhn, Radoslav Mladenov, Eric Aslanian, Dmitrij Hristodorov, Sonja Schiffer
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Antibodies
Subjects:
immunotoxin
CD64
inflammation
mouse model
Online Access:http://www.mdpi.com/2073-4468/2/1/9

Internet

http://www.mdpi.com/2073-4468/2/1/9

Similar Items