The mitotic arrest deficient protein MAD2B interacts with the clathrin light chain A during mitosis.

BACKGROUND: Although the mitotic arrest deficient protein MAD2B (MAD2L2) is thought to inhibit the anaphase promoting complex (APC) by binding to CDC20 and/or CDH1 (FZR1), its exact role in cell cycle control still remains to be established. METHODOLOGY/PRINCIPAL FINDINGS: Using a yeast two-hybrid i...

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Main Authors: Klaas Medendorp, Lilian Vreede, Jan J M van Groningen, Lisette Hetterschijt, Linda Brugmans, Patrick A M Jansen, Wilhelmina H van den Hurk, Diederik R H de Bruijn, Ad Geurts van Kessel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994903?pdf=render