Generation of an ESRG Pr-tdTomato reporter human embryonic stem cell line, CSUe011-A, using CRISPR/Cas9 editing

ESRG was first identified in our previous study. It is highly expressed in human embryonic stem cells (hESCs), whereas it is significantly down-regulated in differentiated cells and is undetectable in adult tissues. To develop an hESC line for monitoring the expression of ESRG for further study of i...

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Bibliographic Details
Main Authors: Hui Liu, Shasha Li, Caiping Ren, Weidong Liu, Bin Zhu, Lei Wang, Hongjuan Xu, Wen Xie, Xiang Zuo, Yao Zhou, Longlong Luo, Xingjun Jiang
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120302841