Ephrin-A5 suppresses neurotrophin evoked neuronal motility, ERK activation and gene expression.

During brain development, growth cones respond to attractive and repulsive axon guidance cues. How growth cones integrate guidance instructions is poorly understood. Here, we demonstrate a link between BDNF (brain derived neurotrophic factor), promoting axonal branching and ephrin-A5, mediating axon...

Full description

Bibliographic Details
Main Authors: Christin Meier, Sofia Anastasiadou, Bernd Knöll
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3191169?pdf=render