Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells

Bleomycin Inhibits Proliferation via Schlafen-Mediated Cell Cycle Arrest in Mouse Alveolar Epithelial Cells

Background Idiopathic pulmonary fibrosis involves irreversible alveolar destruction. Although alveolar epithelial type II cells are key functional participants within the lung parenchyma, how epithelial cells are affected upon bleomycin (BLM) exposure remains unknown. In this study, we determined w...

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Bibliographic Details
Main Authors: Soojin Jang, M.S., Se Min Ryu, M.D., Ph.D., Jooyeon Lee, M.S., Hanbyeol Lee, M.S., Seok-Ho Hong, Ph.D., Kwon-Soo Ha, Ph.D., Won Sun Park, Ph.D., Eun-Taek Han, Ph.D., Se-Ran Yang, D.V.M., Ph.D.
Format: Article
Language:English
Published: The Korean Academy of Tuberculosis and Respiratory Diseases 2019-04-01
Series:Tuberculosis and Respiratory Diseases
Subjects:
idiopathic pulmonary fibrosis
alveolar epithelial cells
cell cycle arrest
schlafen
bleomycin
Online Access:https://www.e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0124&code=0003TRD&vmode=FULL

Internet

https://www.e-trd.org/search.php?where=aview&id=10.4046/trd.2017.0124&code=0003TRD&vmode=FULL

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