Interneuronal Transfer and Distal Action of Tetanus Toxin and Botulinum Neurotoxins A and D in Central Neurons

Recent reports suggest that botulinum neurotoxin (BoNT) A, which is widely used clinically to inhibit neurotransmission, can spread within networks of neurons to have distal effects, but this remains controversial. Moreover, it is not known whether other members of this toxin family are transferred...

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Bibliographic Details
Main Authors: Ewa Bomba-Warczak, Jason D. Vevea, Joel M. Brittain, Annette Figueroa-Bernier, William H. Tepp, Eric A. Johnson, Felix L. Yeh, Edwin R. Chapman
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716309275