Prevention of CpG-induced pregnancy disruption by adoptive transfer of in vitro-induced regulatory T cells.
OBJECTIVE: To elucidate the mechanism by which embryo-resorption and preterm birth were enhanced by pathogenic CpG motif and to develop a counter strategy for normal pregnancy outcome. METHODS: This is an animal model-based study. In pregnant nonobese diabetic (NOD) mice and wild-type (WT) mice in t...
Main Authors: | Yi Lin, Xiaorui Liu, Bin Shan, Ji Wu, Surendra Sharma, Yun Sun |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3979847?pdf=render |
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