Prevention of CpG-induced pregnancy disruption by adoptive transfer of in vitro-induced regulatory T cells.

OBJECTIVE: To elucidate the mechanism by which embryo-resorption and preterm birth were enhanced by pathogenic CpG motif and to develop a counter strategy for normal pregnancy outcome. METHODS: This is an animal model-based study. In pregnant nonobese diabetic (NOD) mice and wild-type (WT) mice in t...

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Bibliographic Details
Main Authors: Yi Lin, Xiaorui Liu, Bin Shan, Ji Wu, Surendra Sharma, Yun Sun
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3979847?pdf=render