Iron Overload Mimicking Conditions Skews Bone Marrow Dendritic Cells Differentiation into MHCII<sup>low</sup>CD11c<sup>+</sup>CD11b<sup>+</sup>F4/80<sup>+</sup> Cells

Iron Overload Mimicking Conditions Skews Bone Marrow Dendritic Cells Differentiation into MHCII<sup>low</sup>CD11c<sup>+</sup>CD11b<sup>+</sup>F4/80<sup>+</sup> Cells

Iron overload is an undesired effect of frequent blood transfusions or genetic diseases. Myelodysplastic syndrome (MDS) patients become transfusion dependent, but due to the combination of ineffective haematopoiesis and repeated blood transfusions they are often subject to iron overload. In this stu...

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Bibliographic Details
Main Authors: Giulio Verna, Marina Liso, Stefania De Santis, Manuela Dicarlo, Elisabetta Cavalcanti, Alberto Crovace, Annamaria Sila, Pietro Campiglia, Angelo Santino, Antonio Lippolis, Grazia Serino, Alessio Fasano, Marcello Chieppa
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
dendritic cells
inflammation
iron overload
bone marrow
Online Access:https://www.mdpi.com/1422-0067/21/4/1353

Internet

https://www.mdpi.com/1422-0067/21/4/1353

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