Deficiency in Neuroserpin Exacerbates CoCl2 Induced Hypoxic Injury in the Zebrafish Model by Increased Oxidative Stress

Deficiency in Neuroserpin Exacerbates CoCl2 Induced Hypoxic Injury in the Zebrafish Model by Increased Oxidative Stress

Protective strategy against hypoxic-ischemic (H/I) induced injury has been intensively discussed. Neuroserpin, an inhibitor for tissue plasminogen activator (tPA), has been proved a vital neuroprotective agent in cerebral ischemia mouse model and oxygen-glucose deprivation and reoxygenation (OGD/R)...

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Bibliographic Details
Main Authors: Sha Han, Dongyang Zhang, Qiang Dong, Xu Wang, Liang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Pharmacology
Subjects:
neuroserpin
cobalt chloride (CoCl2)
hypoxia
protective
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.632662/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.632662/full

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