BCR/ABL1 fluorescence <em>in situ</em> hybridization fusion signals on both copies of chromosome 22 in a Philadelphia-masked chronic myeloid leukemia case: implication for the therapy

BCR/ABL1 fluorescence <em>in situ</em> hybridization fusion signals on both copies of chromosome 22 in a Philadelphia-masked chronic myeloid leukemia case: implication for the therapy

The cytogenetic hallmark of Chronic Myeloid Leukemia (CML) is the presence of Philadelphia (Ph) chromosome, which results from a reciprocal translocation t(9;22)(q34;q11). In this report, we describe a CML patient with no evidence of Ph chromosome but trisomy of chromosome 8 as single cytogenetic a...

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Bibliographic Details
Main Authors: Silvia Soriani, Valentina Guido, Giambattista Bertani, Clara Cesana, Valentina Motta, Gabriella De Canal, Elena De Paoli, Silvio Veronese, Emanuela Bonoldi, Lorenza Romitti
Format: Article
Language:English
Published: PAGEPress Publications 2021-03-01
Series:Hematology Reports
Subjects:
Chronic Myeloid Leukemia
CML
Philadelphia chromosome-negative
masked Philadelphia
p.(Tyr315Ile) mutation
Online Access:https://www.pagepress.org/journals/index.php/hr/article/view/8795

Internet

https://www.pagepress.org/journals/index.php/hr/article/view/8795

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