Study of the HIV-2 Env cytoplasmic tail variability and its impact on Tat, Rev and Nef.

BACKGROUND:The HIV-2 env's 3' end encodes the cytoplasmic tail (CT) of the Env protein. This genomic region also encodes the rev, Tat and Nef protein in overlapping reading frames. We studied the variability in the CT coding region in 46 clinical specimens and in 2 reference strains by seq...

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Bibliographic Details
Main Authors: Nordine Bakouche, Anne-Thérèse Vandenbroucke, Patrick Goubau, Jean Ruelle
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3815105?pdf=render