Limitations of the incidence density ratio as approximation of the hazard ratio

Limitations of the incidence density ratio as approximation of the hazard ratio

Abstract Background Incidence density ratios (IDRs) are frequently used to account for varying follow-up times when comparing the risks of adverse events in two treatment groups. The validity of the IDR as approximation of the hazard ratio (HR) is unknown in the situation of differential average fol...

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Bibliographic Details
Main Authors: Ralf Bender, Lars Beckmann
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Trials
Subjects:
Hazard function
Incidence rate
Incidence density ratio
Randomized controlled trials
Simulation
Time-to-event data
Online Access:http://link.springer.com/article/10.1186/s13063-019-3590-2

Internet

http://link.springer.com/article/10.1186/s13063-019-3590-2

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