Four-Year Longitudinal Study of Motor and Non-motor Symptoms in LRRK2-Related Parkinson's Disease

Objectives: In a prospective 4-year study, we evaluated the progression of motor and non-motor symptoms in Parkinson's disease (PD) patients with Asian-specific LRRK2 risk variants and non-carriers.Methods: A total of 202 patients with PD, including 133 risk variant carriers and 69 non-carriers...

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Bibliographic Details
Main Authors: Xiao Deng, Bin Xiao, Hui-Hua Li, Ebonne Ng, Yew-Long Lo, Eng-King Tan, Kumar M. Prakash
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01379/full