Molecular identification of Sicilian (<FONT FACE=Symbol>dß)º-thalassemia associated with ß-thalassemia and hemoglobin S in Brazil</FONT>

Molecular identification of Sicilian (<FONT FACE=Symbol>dß)º-thalassemia associated with ß-thalassemia and hemoglobin S in Brazil</FONT>

We describe the clinical and molecular characteristics of two unrelated Brazilian families with an association of the Sicilian form of (dß)º-thalassemia with hemoglobin S and ß-thalassemia. Direct sequencing of the ß-globin gene showed only the hemoglobin S mutation in patient 1 and the ß-thalassemi...

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Bibliographic Details
Main Authors: T.G. de Andrade, A. Fattori, S.T.O. Saad, M.F. Sonati, F.F. Costa
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2002-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Thalassemia
Sickle cell
Hereditary persistence of fetal hemoglobin
Globin genes
Sicilian thalassemia
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800003&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000800003&lng=en&tlng=en

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