Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension

Krüppel-like Factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension

<p/> <p>Background</p> <p>Pulmonary arterial hypertension (PAH) is a vascular remodeling disease characterized by enhanced proliferation of pulmonary artery smooth muscle cell (PASMC) and suppressed apoptosis. This phenotype has been associated with the upregulation of the on...

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Bibliographic Details
Main Authors: Paulin Roxane, Bisserier Malik, Chapolard Mathilde, Jacob Maria, Meloche Jolyane, Barrier Marjorie, Tremblay Véronique L, Courboulin Audrey, Lambert Caroline, Provencher Steeve, Bonnet Sébastien
Format: Article
Language:English
Published: BMC 2011-09-01
Series:Respiratory Research
Subjects:
Pulmonary arterial hypertension
KLF5
STAT3
proliferation
apoptosis.
Online Access:http://respiratory-research.com/content/12/1/128

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http://respiratory-research.com/content/12/1/128

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