Enzyme kinetics and inhibition parameters of human leukocyte glucosylceramidase

Enzyme kinetics and inhibition parameters of human leukocyte glucosylceramidase

Glucosylceramidase (GCase) is a lysosomal enzyme that catalyzes the cleavage of β-glucosidic linkage of glucocerebroside (GC) into glucose and ceramide; thereby, plays an essential function in the degradation of complex lipids and the turnover of cellular membranes.The growing list of 460 mutations...

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Bibliographic Details
Main Authors: Mesut Karatas, Senol Dogan, Emrulla Spahiu, Adna Ašić, Larisa Bešić, Yusuf Turan
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Heliyon
Subjects:
Proteins
Biochemistry
Molecular biology
Hematological system
Clinical research
Glucosylceramidase
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402032034X

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http://www.sciencedirect.com/science/article/pii/S240584402032034X

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