CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair
The integration of exogenous DNA into the genome using CRISPR–Cas9 often presents a challenge to researchers. Here the authors fuse CtIP to Cas9 to stimulate recombination at target loci.
Bibliographic Details
| Main Authors: |
M. Charpentier,
A. H. Y. Khedher,
S. Menoret,
A. Brion,
K. Lamribet,
E. Dardillac,
C. Boix,
L. Perrouault,
L. Tesson,
S. Geny,
A. De Cian,
J. M. Itier,
I. Anegon,
B. Lopez,
C. Giovannangeli,
J. P. Concordet |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-03475-7
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