In vitro characterization of the effects of chronic insulin stimulation in mouse 3T3-L1 and human SGBS adipocytes

Hyperinsulinemia is the hallmark of the development of insulin resistance and precedes the diagnosis of type 2 diabetes. Here we evaluated the effects of prolonged exposure (≥4 days) to high insulin doses (150 nM) in vitro in two adipose cell types, mouse 3T3-L1 and human SGBS. Chronic insulin treat...

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Bibliographic Details
Main Authors: A. Rossi, M. Eid, J. Dodgson, G. Davies, B. Musial, M. Wabitsch, C. Church, D.C. Hornigold
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Adipocyte
Subjects:
Online Access:http://dx.doi.org/10.1080/21623945.2020.1798613