MTHFD1L, A Folate Cycle Enzyme, Is Involved in Progression of Colorectal Cancer

Identification of new molecular targets is needed for the treatment of colorectal cancer (CRC). Methylenetetrahydrofolate dehydrogenase 1 like (MTHFD1L), an enzyme in the folate cycle, is involved in formate generation and therefore in one-carbon metabolism. Here, we examined the expression and the...

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Bibliographic Details
Main Authors: Sumit Agarwal, Michael Behring, Kevin Hale, Sameer Al Diffalha, Kai Wang, Upender Manne, Sooryanarayana Varambally
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523319302293