Exogenous LIN28 Is Required for the Maintenance of Self-Renewal and Pluripotency in Presumptive Porcine-Induced Pluripotent Stem Cells

Exogenous LIN28 Is Required for the Maintenance of Self-Renewal and Pluripotency in Presumptive Porcine-Induced Pluripotent Stem Cells

Porcine species have been used in preclinical transplantation models for assessing the efficiency and safety of transplants before their application in human trials. Porcine-induced pluripotent stem cells (piPSCs) are traditionally established using four transcription factors (4TF): OCT4, SOX2, KLF4...

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Bibliographic Details
Main Authors: Warunya Chakritbudsabong, Somjit Chaiwattanarungruengpaisan, Ladawan Sariya, Sirikron Pamonsupornvichit, Joao N. Ferreira, Panithi Sukho, Dulyatad Gronsang, Theerawat Tharasanit, Andras Dinnyes, Sasitorn Rungarunlert
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
LIN28
reprogramming
induced pluripotent stem cells
porcine
self-renewal
pluripotency
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.709286/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.709286/full

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