Human Papillomaviruses Preferentially Recruit DNA Repair Factors to Viral Genomes for Rapid Repair and Amplification

High-risk human papillomaviruses (HPVs) activate the ataxia telangiectasia mutated-dependent (ATM) DNA damage response as well as the ataxia telangiectasia mutated-dependent DNA-related (ATR) pathway in the absence of external DNA damaging agents for differentiation-dependent genome amplification. T...

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Bibliographic Details
Main Authors: Kavi Mehta, Laimonis Laimins, Michael J. Imperiale
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/1/e00064-18