Identification of Sialyl-Lewis(x)-Interacting Protein on Human Spermatozoa

Identification of Sialyl-Lewis(x)-Interacting Protein on Human Spermatozoa

Capacitated spermatozoa initiate fertilization by binding to the zona pellucida (ZP). Defective spermatozoa-ZP binding causes infertility. The sialyl-Lewis(x) (SLeX) sequence is the most abundant terminal sequence on the glycans of human ZP glycoproteins involving in spermatozoa-ZP binding. This stu...

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Bibliographic Details
Main Authors: Ying Wang, Weie Zhao, Si Mei, Panyu Chen, Tsz-Ying Leung, Cheuk-Lun Lee, William S. B. Yeung, Jian-Ping Ou, Xiaoyan Liang, Philip C. N. Chiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
zona pellucida
human spermatozoa
sialyl-Lewis(x)
C1orf56
fertilization rate
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.700396/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.700396/full

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