Quantitative peptidomics of Purkinje cell degeneration mice.

Quantitative peptidomics of Purkinje cell degeneration mice.

Cytosolic carboxypeptidase 1 (CCP1) is a metallopeptidase that removes C-terminal and side-chain glutamates from tubulin. The Purkinje cell degeneration (pcd) mouse lacks CCP1 due to a mutation. Previously, elevated levels of peptides derived from cytosolic and mitochondrial proteins were found in a...

Full description

Bibliographic Details
Main Authors: Iryna Berezniuk, Juan J Sironi, Jonathan Wardman, Raymond C Pasek, Nicolas F Berbari, Bradley K Yoder, Lloyd D Fricker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620535?pdf=render

Internet

http://europepmc.org/articles/PMC3620535?pdf=render

Similar Items