Impairment of cold injury-induced muscle regeneration in mice receiving a combination of bone fracture and alendronate treatment.

Alendronate, a nitrogen-containing bisphosphonate, is well established as a treatment for osteoporosis through regulation of osteoclast activity. Previously, the pharmacological effects of bisphosphonates on cells outside the bone environment have been considered irrelevant because bisphosphonates t...

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Bibliographic Details
Main Authors: Shigeo Kawada, Atsushi Harada, Naohiro Hashimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5513540?pdf=render